Author: denialism_bv2x6a

  • Berkeley's New Monument to Itself [Updated]

    So, here it is. Titled “Berkeley’s Big People,” it is installed along I-80, so those of you driving north of San Francisco will probably see it, as it is 30 feet tall and visible from a mile away.

    Given the landscape of “free speech,” it would have been much more appropriate to have erected a large Don Quixote, fending off autism-causing vaccines, and tilting at a windmill atop a stolen shopping basket full of junk but missing it because he was high. And then declaring victory.

    Updates: my Berkeley friends respond! All of these responses are incredibly valuable, so you are to be subjected to them now!

    AC asks: “‘lower sproul plaza drumming circle’ is listed as a cultural contribution?”

    and then remarks: “mmm … i think you should round up some little people and protest the name. it’s offensive.”

    BG remarks that after victory is declared, the statute should depict: “…pooping on the street!”

  • Health priorities

    I made a mistake. First, I got a little worked up during last night’s debate because, when discussing health problems, both candidates gave shout-outs to relatively rare conditions rather than to the big killers. My second mistake was more grievous. I read something in HuffPo written by Deirdre Imus.

    No one brings the stupid quite like Deirdre. When she talks about health, it’s like a 12th century peasant talking about quantum mechanics—-most of the time, she’s not even wrong.

    Deirdre’s upset. She’s upset that the candidates haven’t addressed children’s healt issues. That’s reasonable.

    Anticipating the lack of attention always given to children, last April I sent a questionnaire to both Senators McCain and Obama in order to elicit their positions and strategies “to address children’s health issues.”

    Despite numerous calls to both campaign offices, neither has had the courtesy to respond to a few specific questions that are critically important to millions of parents and could garner millions of votes.

    Perhaps the candidates don’t care about kids. Or perhaps the candidates strategically feel that these issues won’t get them the votes.

    Or maybe they just think Imus is a crackpot.

    She was upset about not hearing back from the candidates, so she posted her questionnaire online. After reading it, I’m pretty sure I understand why it was ignored.

    (more…)

  • Why should I trust you?

    On call one night as a medical student, I was presenting a case to my intern. As I recounted the patient’s ER course, the intern stopped me and said, “Pal — trust no one.”

    That sounded a little harsh to me, but the intern was nice enough to explain further.

    “Look, you’re going to be taking calls from doctors and nurses the rest of your career. They are going to give you information about a patient, but it’s you who will be responsible for everything that goes right and wrong. Do you want to hang yourself on someone else’s evaluation?”

    As any internist knows, there is a perpetual tension between ER and internal medicine docs. ER docs need to save lives and move meat. The snapshot the ER doc gets is sometimes inconsistent with the bigger picture the internist sees, leading to some conflict. It’s inevitable, really, that how the patient looks in the ER will differ from how they are up on the floor several hours later. And this is what my intern was conveying to me.

    Patients will often complain about the parade of students, interns, residents, and attendings who seem to ask the same set of questions, but this was my intern’s point: things change, stories change, clinical facts change, and you better make sure the facts you report are the facts you verified.

    (As an aside, it’s a not infrequent occurrence that a patient’s story will change significantly with the length of the white coat. The indigestion the student hears about becomes the crushing sub-sternal chest pain the attending rushes to the cath lab.)

    I also remind patients that they don’t know which one of us might be called to their bedside in the middle of the night, so it’s best tolerate us all.

    Anyway, this is my long-winded way of getting to the issue of trust. There are ER doctors who I’ve worked with for years and I know pretty well. I know their quirks, and I know that what they tell me is how it is (at that particular moment).

    If I get an ER call from someone I don’t know, I will listen politely, but I’m probably going to see that patient first and re-check everything myself.

    So “trust no one” isn’t precisely the dictum, but it’s a start. Clearly level of trust is influenced by many different factors.

    At January’s ScienceOnline09 conference, Terra Sig’s Abel Pharmboy and I will be hosting a session on blogging and anonymity. It’s a topic particularly important to us as bloggers of medical science. A number of months ago, I “unmasked” myself and never really explained to anyone why. Pseudonyms are a big part of blog culture, and I preferred to keep mine while no longer guarding my real identity (for various reasons).

    I would argue that in the blogosphere, there are three levels of identity: real name identity, pseudonymity, and anonymity. Real name identity is still not the “real person”. People write and behave differently online. Pseudonymity (my particular choice) involves using a pseudonym, but having one’s true name generally known or available. Anonymity is just that—the attempt to keep your real life identity completely secret. Each of these levels has different implications on both how the writer behaves and how the reader perceives.

    Abel has brought the issue of trust forward—both the reader’s trust of the blogger, and the blogger’s trust in the reader. At our session (which we’d love to have you at, but will probably blog about, or better yet, maybe we’ll live blog it and take questions) I’m sure we’ll address lots of these issues, but we’d like to hear from denizens of the blogosphere. Abel’s question was, “do you trust me?” My question to you is, “Do you consider blogger identity when reading, and if so how? And do you find there to be a difference in the three levels of identity?”

    Or of course, ignore my question, and say whatever you wish.

  • Tissue is the issue–revised version

    NB: images in this post are thought to be in the public domain, but were not well labeled, so if you feel they have been posted without proper attribution, please email me or leave a comment. Thanks. Also, this is a revision of a post from yesterday which I’ve pulled secondary to ethical concerns. I’ve deleted the comments so we can start out fresh. –PalMD

    I can’t seem to get this whole “morgellons” thing out of my head (which gives me something in common with the sufferers). Lots of the “literature” on morgellons focuses on the “fibers” which supposedly infest these people. If you google it, you can get pictures galore of these fibers. The advocacy websites are also full of stories of “fiber analysis” from law enforcement. I’m not much for crime lab analyses when it comes to human pathology. Show me the tissue!

    If morgellons were a disease as such, it would cause pathologic changes in the tissue affected. These should be visible on both a gross an microscopic level. Let me show you what I mean.

    A young woman came to see me a few years back with a rash. She had rashes in the past—poison ivy, mosquito bites, chicken pox—but this one was different. It was all over her legs, many of the bumps were raised, and it was spreading quickly.

    (more…)

  • Here Comes the Downturn Denialism

    We have not played with the Denialists’ Deck of Cards for some time! Let’s pick them up again, because the economic downturn gives all sorts of businesses the opportunity to play the “Bear Market” card.

    i-e9c987e71f4415eb0c74e05a507bc833-qc.jpgStephen Power brings it in today’s Wall Street Journal:

    “We know something needs to be done [to cut emissions], but we’ve got to get the economy on its feet before we do something economically irrational,” said Mike Morris, chief executive of American Electric Power Co. of Columbus, Ohio. Mr. Morris and other executives fear lawmakers will use revenue from pollution permits to pay down the federal deficit.

    “The likelihood that they would try to take these revenues for other purposes, particularly in an economic downturn, is great,” says James Rogers, chief executive of North Carolina-based Duke Energy Corp.


    Do not feel so bad for these guys, because when the markets are up, they play “Bull Market.” If the market is doing well, you should not mess with success.

  • Hmm…ethics…

    Ok, I pulled my post while considering ethical issues, viz this conversation:

    Dianne, PAL:

    I’m out of my depth here, so could you address what the ethical boundaries are for describing a case (even without personal identification) on an open board?

    I’ve always dealt with that one by Just Don’t — and I know it’s overly conservative. And I promise to not take you as too authoritative, but it’s an interesting subject …

    Posted by: D. C. Sessions | October 15, 2008 9:09 PM

    Well, it’s an interesting issue. Generally, cases are fine to present as long as enough details are changed. Given that I’ve lived/practiced in a number of different cities/states, and that the only real identifying info is that the patient is a male in his 60s (which may or may not be true), and i’ve presented a picture that may or may not be the actual patient, the ethics seem to be in my favor.

    NEJM, for example, is a publicly available journal, and regularly presents cpc’s without identifying info.

    Curse/bless you for bringing this up.

    Case presentations are not in and of themselves unethical. The ethical issues involve what is in the patient’s best interest. If a patient is not identifiable, there should be no ethical issue.

    Except when there is.

    Some would argue that a patient can be ethically harmed even if they are not identified, as the information about them belongs to them, and is theirs to hold or release. This, I think, is where the issue of mixing up case details comes in. If the details are not traceable to a particular patient, then there is no harm.

    However, since I am talking about a path report, one could argue that there is an ethical problem.

    There is also a question as to what benefit a patient may or may not derive…

    Hmm…

    Posted by: PalMD [TypeKey Profile Page] | October 15, 2008 9:16 PM

    Discuss amongst yourselves while I consult my betters….

  • Breathing 102—bringing the woo

    (This one is cross-posted over at Science-Based Medicine. FYI. –PalMD)

    If you’ve been a regular reader of SBM or denialism blog, you know that plausibility plays an important part in science-based medicine. If plausibility is discounted, clinical studies of improbable medical claims can show apparently positive results. But once pre-test probability is factored in, the truth is revealed—magic water can’t treat disease, no matter what a particular study may say. So it was with great dismay that I read an email from a reader telling me about parents buying hyperbaric chambers for their autistic children. Let’s review some science.

    In Breathing 101, we talked about how the oxygen delivered to your lungs depends on both the percentage of oxygen in the air, and the air pressure. We looked at how diminishing atmospheric pressure, for example at altitude, makes it harder to breathe.

    Of course it is also possible to expose people to increased atmospheric pressure, which has therapeutic uses in the form of hyperbaric oxygen therapy (HBOT).

    Oxygen delivery to tissue depends on several factors. We already talked about the air itself. Once air gets enters the lungs, most of the oxygen transported to your tissues is carried by the hemoglobin molecules in your red blood cells (under normal conditions). A small amount is directly dissolved in the blood. The amount dissolved in the blood is dependent on (no surprise) the percentage of oxygen and the atmospheric pressure. By increasing the atmospheric pressure from 1 atm (760 torr) to 3 atm, the amount of oxygen dissolved in the blood is enough to meet your body’s needs independent of heme-associated oxygen.

    This is a good thing.

    For example, up here in the Midwest, we have a lot of cases of carbon monoxide (CO) poisoning during the winter. CO binds to hemoglobin much more strongly than oxygen, so even after victims are removed to a normal environment, they are still asphyxiating.

    Carbon monoxide intoxication is one of the primary uses of HBOT. Under pressure, enough oxygen is delivered to the tissues for the patient to survive. Additionally, the increased pressure helps oxygen displace CO so that heme molecules are free to go back to the work of transporting oxygen.

    The original use for HBOT was of course “the bends”. When a person (for example a diver) is exposed to high pressures for a long period of time, nitrogen, which is normally not very soluble in blood, dissolves much more readily. When the diver ascends, the nitrogen bubbles are released from the blood into the tissues, causing widespread damage. HBOT can be used to help a diver “ascend” more slowly, so that the nitrogen comes out of solution in a much less damaging fashion.

    HBOT can also be used to treat a variety of other conditions that are responsive to increased oxygen tension, such as anaerobic bacterial infections. But hyperbaric chambers are not without risk. Small errors can cause big problems, including death.

    Strangely enough, though, you can buy your very own hyperbaric chamber for use in your own home, and parents of autistic children are doing just that.

    So why does anyone think that HBOT might be appropriate for the treatment of autism? Is it even plausible? Autism spectrum disorder (ASD) is a very broad diagnostic category. Autism is a neurobehavioral disorder of inconsistent severity and unknown cause. There has been some decent research into etiology, and in some cases genetic causes have been implicated. There is no reason to suspect that autism has anything to do with decreased oxygen tension.

    As you have no doubt read in this space, autism attracts a wide range of quackery, and HBOT for autism is quacks pretty loudly.

    Whose idea is this, anyway?

    All signs point to a guy named Dan Rossignol. Dr. Rossignol is apparently into every form of autism crankery, including mercury poisoning, mitochondrial dysfunction, and oxidative stress (although I can’t imagine that increased PaO2 is an effective treatment for “oxidative stress”). After spending a few minutes looking through is web-based material, I’m starting to think that this guy can give the Geier’s a run for their money.

    (more…)

  • Who broke ScienceBlogs?

    Yeah, we know things aren’t working right. Comments are timing out, but that’s the least of it. Our techies aren’t sure yet what’s going on, but they are putting extra hamsters on the treadmill working extra hard trying to get things moving smoothly again.

    Meanwhile, if you comment and it times out on you, don’t worry, it probably went through.

    Stay tuned…

  • Breathing 101

    A letter from a reader (thank you, Mr. “Smith”) got me thinking—could the fight against improbable medical claims be aided by a better knowledge of science? In another attempt to bring complicated science to the masses, today we will learn a bit about how we breathe. The first thing we need to understand is what we breathe.

    Let us speak of air. We know we need it. Most of us know that the oxygen that makes up about twenty percent of it is necessary for life. If you think a little bit more, you probably realize that in addition to the oxygen content, there is another variable that is critical in making air breathable. When we climb a mountain or get in a plane, the air is less breathable. Why is that? The air up there is still 21% oxygen, so what’s the deal?

    (more…)

  • Is this for real? Racist attacks on Obama from all sides

    I hate having to repost this but there’s a reason. If you watch the GOP rally’s lately, they are becoming filled with hate, with near-violence, with hyperbole calling Obama as terrorist. McCain isn’t my candidate, but that’s it—I may not agree with him, but I know he’s no terrorist; I know he’s not evil. But the GOP is now explicitly calling up it’s more violent, racist base in its desperate attempt to claw its way back to the top.

    A lot of folks around here like primates. In fact, all of the bloggers around here are primates. So a number of us are pretty riled up about a recent story out of Georgia (although I don’t advocate another apocalyptic March to the Sea). There is another poll to crash with the linked story, so go have at it.

    In a similar vein, I posted a piece on my old blog a little while back about an article that wasn’t written by an ignorant redneck, but by a writer for a prominent conservative news outlet. What follows is the repost.
    (more…)